Tetrapyrroles and derivatives
Cayman Chemical MethylcobalamIn 500mg
An analog of vitamin B12 with diverse neurological activities; promotes neurite outgrowth and survival in primary CGN and DRG cells and activation of ERK1/2 and Akt from 0.1-100 µM; improves sensory function in a pinch test and increases toe spreading in a rat model of sciatic nerve injury at 1 mg/kg per day; decreases the number of atypical mitochondria in the sciatic nerve and reduces vincristine-induced mechanical allodynia and thermal hyperalgesia in a rat model of neuropathic pain; reduces muscle weakness and forelimb contracture and increases bicep muscle weight and the number of musculocutaneous nerves in the wobbler mouse model of ALS; enhances the recovery of compound muscle action potentials and motor end plate innervation and decreases the time to sticker removal in the sticker removal grooming test in a rat model of bicep ulnar to musculocutaneous nerve transfer
Frontier Specialty Chemicals 250MG BILIVERDIN HYDROCHLORIDE
Biliverdin hydrochloride; CAS No: 55482-27-4
Sigma Aldrich Fine Chemicals Biosciences Methylcobalamin vitamin B125MG
Methylcobalamin (MeCbl) is an analog of vitamin B12 (cobalamin). It differs from cobalamin by containing a methyl group. The physiologically active form of vitamin B12 include methylcobalamin and adenosylcobalamin.
Medchemexpress LLC Cyanocobalamin | 68-19-9 | 99.95% | 50 MG
Vitamin B12 (Standard) is an analytical standard of Vitamin B12. It is intended for research and analytical applications, playing a key role in the normal functioning of the brain and nervous system, and for the formation of blood. This compound is of analytical standard grade and serves as a reference standard for assays.
- Intended for research and analytical applications
- Plays a key role in brain and nervous system function
- Important for blood formation
- Serves as a reference standard for assays
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Abcam 5-Aza-2'-deo x ycytidine (Decitabine), DNMT1 inhibitor, 25MG
MW 228.21 Da, Purity >99%. Potent DNA methyltransferase 1 (DNMT1) inhibitor (IC₅₀ = 0.2 μM). Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows antimetabolic and anticancer activities in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 505124, ALK5 inhibitor, 5MG
MW 335.4 Da, Purity >98%. Potent, reversible, competitive ALK5 inhibitor (IC₅₀ values are 47 and 129 nM for ALK5 and ALK4 respectively). Inhibits ALK7 but not ALK1, 2, 3, or 6. Shows antifibrotic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam UCPH-101, Selective EAAT1 inhibitor, 1MG
MW 422.5 Da, Purity >98%. Selective inhibitor of EAAT1 (IC₅₀ = 0.67 μM). Displays >400-fold selectivity over EAAT2 and EAAT3. Blood-brain barrier permeable analog UCPH-102 also available (ab146404).
The product is subject to the following: Abcam Restricted Use Statement