Tetrapyrroles and derivatives
Sigma Aldrich Fine Chemicals Biosciences Cyanocobalamin (crystallline) United States Pharmacopeia (USP) Reference Standard | 68-19-9 | 2X150MG
Cyanocobalamin (crystallline) United States Pharmacopeia (USP) Reference Standard | Mol Wt: 1355.37 | 68-19-9 | 2X150MG
Medchemexpress LLC Vitamin B12 | 68-19-9 | 99.99% | 1 ML
Vitamin B12 (Cyanocobalamin) is a crucial vitamin involved in the metabolism of every cell, particularly affecting DNA synthesis, fatty acid synthesis, and energy production. It plays a key role in brain and nervous system function, and blood formation, offering protection against oxidative stress and benefiting inflammatory diseases.
- Passes through the blood-brain barrier
- Involved in cell metabolism
- Supports DNA synthesis and regulation
- Aids in fatty acid synthesis and energy production
- Beneficial for inflammatory diseases
- Provides protection in oxidative-stress-associated pathologies
Medchemexpress LLC Methylcobalamin | 13422-55-4 | 99.0% | 1 ML
Methylcobalamin, a cobalamin and form of vitamin B12, is characterized by a methyl group replacing the cyanide found in cyanocobalamin. This compound features an octahedral cobalt(III) centre and is known for its rare metal-alkyl bonds. Physiologically, it functions as vitamin B12, addressing deficiencies such as pernicious anemia, and is also applied in treating peripheral neuropathy, diabetic neuropathy, and amyotrophic lateral sclerosis.
- Form of vitamin B12 (cobalamin)
- Contains a methyl group instead of cyanide
- Features an octahedral cobalt(III) centre and metal-alkyl bonds
- Equivalent to vitamin B12 for treating deficiencies (e.g., pernicious anemia)
- Used in peripheral neuropathy, diabetic neuropathy, and amyotrophic lateral sclerosis treatment
Sigma Aldrich Fine Chemicals Biosciences Coenzyme B12 >=97.0% | 13870-90-1 | MFCD00135609 | 1G
Coenzyme B12 >=97.0% | Purity: >=97.0% | Mol Wt: 1579.58 | 13870-90-1 | MFCD00135609 | 1G
Cayman Chemical MethylcobalamIn 100mg
An analog of vitamin B12 with diverse neurological activities; promotes neurite outgrowth and survival in primary CGN and DRG cells and activation of ERK1/2 and Akt from 0.1-100 µM; improves sensory function in a pinch test and increases toe spreading in a rat model of sciatic nerve injury at 1 mg/kg per day; decreases the number of atypical mitochondria in the sciatic nerve and reduces vincristine-induced mechanical allodynia and thermal hyperalgesia in a rat model of neuropathic pain; reduces muscle weakness and forelimb contracture and increases bicep muscle weight and the number of musculocutaneous nerves in the wobbler mouse model of ALS; enhances the recovery of compound muscle action potentials and motor end plate innervation and decreases the time to sticker removal in the sticker removal grooming test in a rat model of bicep ulnar to musculocutaneous nerve transfer
Medchemexpress LLC Bilirubin conjugate disodium | 68683-34-1 | MFCD00044931 | 95.0% | C37H44N6Na2O10S2 | 10MG
Bilirubin conjugate disodium is a water-soluble, ditaurate derivative of bilirubin used as a research reagent and drug-metabolite reference for studies of heme metabolism and assay development. The material is supplied as the disodium salt (C37H44N6Na2O10S2) and is accompanied by analytical documentation for laboratory use.
- High purity (95.0%).
- Water-soluble disodium salt for aqueous assays.
- Suitable as a reference standard in bilirubin and drug-metabolite studies.
- Provided with certificate of analysis and safety data sheet.
- Available in small quantity packages for research applications.
Frontier Specialty Chemicals 100MG BILIVERDIN HYDROCHLORIDE
Biliverdin hydrochloride; CAS No: 55482-27-4
Abcam DPDPE, delta opioid receptor agonist, 5MG
MW 645.79 g/mol, Purity >95%. Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-745870 trihydrochloride, brain penetrant D4 antagonist, 50MG
MW 436.21 g/mol, Purity >99%. Highly potent and selective D₄ antagonist (Ki values are 0.43, 2300 and 960 nM at D₄, D₃ and D₂, respectively). Brain permeable. Inhibits cell death and shows neuroprotective effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x E-991 dihydrochloride, KCNQ channel blocker; blocks M current, 50MG
MW 449.4 Da, Purity >99%. Potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks M current. (IC₅₀ values are 0.98 μM (M-current), 0.71 μM (KCNQ 2), 0.75 μM (KCNQX 1), >100 μM (Kv1.2) and >43 μM (Kv4.3). Potent pulmonary vasoconstrictor. Cognitive enhancer following oral administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement